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Anti cancer drugs
$400.00 per unit
Temozolomide (pronounced tee-mo-zol-o-mide)
is a chemotherapy drug that is given as a treatment for some types of cancer. It is most commonly used to treat a type of brain tumour known as a glioma. This information describes temozolomide, how it is given and some of its possible side effects. It should ideally be read with our general information about chemotherapy and about your type of cancer. If you have any further questions you can ask your doctor or nurse at the hospital where you are having your treatment, or speak to one of our cancer support service nurses.
How it is given:-
The capsules should be swallowed whole with plenty of water and be taken at the same time every day on an empty stomach. It is important to make sure that you take the capsules exactly as you have been directed by your doctor.
Possible side effects:-
Each person's reaction to chemotherapy is different. Some people have very few side effects, while others may experience more. The side effects described in this information will not affect everyone who is given temozolomide, and may be different if you are having more than one chemotherapy drug.
Lowered resistance to infection Temozolomide can reduce the production of white blood cells by the bone marrow, making you more prone to infection. This effect can begin seven days after treatment has been given, and your resistance to infection usually reaches its lowest point 10–14 days after chemotherapy. Your blood cells will then increase steadily and will usually have returned to normal levels within 21–28 days.
Contact your doctor or the hospital straightaway if:
Your temperature goes above 38ºC (100.5ºF) You suddenly feel unwell (even with a normal temperature).You will have a blood test before having more chemotherapy to make sure that your cells have recovered. Occasionally it may be necessary to delay your treatment if the number of blood cells (the blood count) is still low. Temozolomide is sometimes given at the same time as a six week course of radiotherapy. Your blood cell count will be monitored throughout the course of treatment to make sure that the number of white blood cells doesn't get too low. Bruising or bleeding Temozolomide can reduce the production of platelets (which help the blood to clot).
Let your doctor know if you have any unexplained bruising or bleeding, such as nosebleeds, blood spots or rashes on the skin, and bleeding gums. Anaemia (low number of red blood cells) While having treatment with temozolomide you may become anaemic. This may make you feel tired and breathless. Let your doctor or nurse know if these are a problem. Nausea (feeling sick) and vomiting If you do feel sick it may begin soon after the treatment is given and may last for approximately 24 hours.
Your doctor can now prescribe very effective anti-sickness (anti-emetic) drugs to prevent or greatly reduce nausea and vomiting. If the sickness is not controlled or continues, tell your doctor, who can prescribe other anti-sickness drugs that may be more effective. Diarrhoea This can usually be easily controlled with medicine but it is important to let your doctor know if it is severe or continues. It is important to drink plenty of fluids if you have diarrhoea. Constipation Constipation can usually be relieved by drinking plenty of fluids, eating a high fibre diet and taking gentle exercise. Sometimes you may need to take medicines to stimulate your bowel. These can be prescribed by your doctor.
Loss of appetite and temporary taste alterations Both of these may occur. A dietitian or specialist nurse at your hospital can give advice on boosting appetite, coping with eating difficulties and maintaining weight. Rashes Temozolomide can cause a rash which may be itchy. Your doctor can prescribe treatment to help reduce this. Headache Let your doctor know if you have headaches while having treatment with temozolomide. Tiredness and feeling weak You may feel very tired. It is important to allow yourself plenty of time to rest.
Less common side effects:-
Hair loss This is rare but hair may thin, or occasionally be lost completely. If hair loss happens, it usually begins 3–4 weeks after starting treatment, although it may occur earlier. It is temporary and your hair will regrow once the treatment is finished. If you are having temozolomide with a course of radiotherapy any hair loss will be due to the radiotherapy and may be permanent.
Dizziness This side effect should be reported to your doctor.
Breathlessness Let your doctor know if breathlessness occurs.
A high temperature and chills These usually do not last for long. Your doctor may prescribe tablets to reduce this side effect.
Other medicines Some medicines can be harmful to take when you are having chemotherapy. Let your doctor know about any medications you are taking, including non-prescribed drugs such as complementary therapies and herbal drugs. Drowsiness Temozolomide may make you drowsy. Take care if you are driving or operating machinery following this treatment. Fertility Your ability to become pregnant or father a child may be affected by taking this drug. You may wish to discuss fertility with your doctor before starting treatment.
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Anti Cancer Formulations
# Product Strength Brand Pack Mode Pack
1 Geftinib 250 mg Geftinat Bottle 30 S
2 Hydroxyurea 500 mg Hyurea Strips 10 S
3 Letrozole 2.5 mg Letronat Strips 10 S
4 Amifostine 500 mg Natfost Vials 1 S
5 Temozolomide 5 mg Temonat Bottles 15 S
6 Temozolomide 20 mg Temonat Bottles 15 S
7 Temozolomide 100 mg Temonat Bottles 5 S
8 Temozolomide 250 mg Temonat Bottles 5 S
9 Imatinib Mesylate 100 mg Veenat Strips 10 S
10 Imatinib Mesylate 100 mg Veenat Bottles 120 S
11 Zoledronic Acid 4 mg Zoldonat Vials 1 S
12 Altretamine 50mg Cantret Strips 10'S
13 Estramustine 140mg Xtrant Bottle 100'S
14 Chlorambucil 2mg Clokeran Bottle 30"S
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